Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 1 of about 1 results

ea0072oc1 | Oral Communications | UKINETS2020

Identification of soluble immune checkpoint receptor landscape in liver metastases of neuroendocrine neoplasms: A new perspective for immunotherapy

Doornebal Ewald , Harris Nicola , Riva Antonio , Pizanias Michail , Phillips Sandra , Zen Yoh , Sticova Eva , Prachalias Andreas , Menon Krishna , Zamalloa Ane , Preziosi Melissa , Heaton Nigel , Eaton Simon , Ramage John , Williams Roger , Palma Elena , Srirajaskanthan Rajaventhan , Chokshi Shilpa

Accumulating evidence suggests that the immunological landscape plays a key role in the progression of neuroendocrine liver metastases (LM-NENs), which is often characterised by immune cell infiltration. Anti-tumour functions of infiltrating lymphocytes are often silenced through hyper-expression of inhibitory checkpoint receptors (CRs) such as PD-1, but favourable outcomes with anti-PD-1 therapy have been low. Recently, functional soluble (cell-free) CRs beyond PD-1 have been...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more